2 citations
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October 2022 in “Journal of Sustainable Materials Processing and Management” This research found that Nano-Transfersomes containing Vitamin E and aloe vera showed improved permeability and prolonged drug release compared to a marketed formulation, with no skin irritancy observed in mice, potentially offering a sustainable and biocompatible option for psoriasis management.
April 2017 in “Journal of Investigative Dermatology” In laboratory tests and mouse models, this study found that the novel IPC analog SIG-1451 may offer potent anti-inflammatory effects for treating allergic skin inflammation, potentially outperforming some current therapies in specific inflammatory phases.
April 2017 in “Journal of Investigative Dermatology” This study found that SM04755, a novel topical drug, inhibited inflammation, keratinocyte proliferation, and fibrosis in vitro and improved skin health in a mouse model of psoriasis, indicating potential as a topical psoriasis treatment.
April 2017 in “Journal of Investigative Dermatology” This study found that fisetin, a dietary flavonoid, significantly improved psoriasiform skin lesions in mice by promoting cell differentiation, inhibiting proliferation, and modulating inflammatory responses.
50 citations
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April 2021 in “Frontiers in Immunology” This review discusses neuroimmune communication in skin disorders and peripheral neuropathic pain, highlighting the complex interactions between sensory neurons and immune cells; it reports no new clinical results but suggests potential future therapies.