19 citations
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September 2019 in “British Journal of Dermatology” This study found that a novel peptide, FOL-005, derived from osteopontin, significantly inhibited hair growth in human hair follicles both ex vivo and in vivo, suggesting potential as a treatment for unwanted hair growth.
5 citations
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June 2024 in “Pharmacological Research” This study identified neuropilin-1 as the receptor for FOL-026 and showed that it stimulates angiogenesis and cell growth, suggesting potential for vascular repair and enhanced angiogenesis therapies.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, FOL-026, a peptide based on osteopontin, was shown to promote angiogenesis and stimulate vascular cell proliferation and migration through neuropilin-1, similar to VEGF, suggesting potential therapeutic applications in vascular repair and angiogenesis-related conditions.
April 2018 in “Journal of Investigative Dermatology” This study identified the osteopontin-derived peptide, FOL-005, as a potential inhibitor of unwanted human hair growth by promoting catagen development without reducing stem cell numbers or showing toxicity.
July 2024 in “Journal of Investigative Dermatology” Combining certain treatments, including FOL005, may improve healing of difficult wounds.