184 citations
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August 1983 in “The journal of pediatrics/The Journal of pediatrics” Biotinidase deficiency has various symptoms and can be treated with biotin supplements.
72 citations
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October 1988 in “Archives of Disease in Childhood” Biotin treatment improves symptoms of biotinidase deficiency, but some neurological damage may be permanent.
43 citations
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April 2005 in “The Journal of Dermatology” Biotin supplements improved skin and hair in a biotin-deficient infant on amino acid formula.
September 1993 in “Archives of Disease in Childhood” Early diagnosis and treatment with biotin are crucial for preventing severe outcomes in certain conditions.
50 citations
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May 1985 in “The journal of pediatrics/The Journal of pediatrics” Biotin deficiency in patients on total parenteral nutrition can cause serious symptoms but can be treated with biotin supplements.