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Glossary Morphogenesis

biological process shaping organism's structure through cell organization

Morphogenesis is the biological process that causes an organism to develop its shape. It involves the coordinated growth, differentiation, and spatial organization of cells and tissues, which ultimately leads to the formation of structures like organs and limbs. This process is crucial in embryonic development and is regulated by genetic and environmental factors.

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Ectodermal Organ Stem Cells: Morphogenesis, Population Regenerative Behavior, and Evolutionary Development

research Ectodermal Organ Stem Cells: Morphogenesis, Population Regenerative Behavior, and Evo-Devo

1 citations , October 2013

This chapter discusses stem cell activity in feather and hair follicles, emphasizing how stem cells maintain their population by cycling between quiescence and activation in specialized niches but reports no new results.

research Organ Culture of Developing Mouse Skin and Its Application for Molecular Mechanistic Studies of Morphogenesis

4 citations , October 2004 in “Humana Press eBooks”

This chapter reports an organ culture method that permits mouse embryonic skin tissues to develop similarly to in vivo conditions, revealing that epidermal growth factor inhibits hair follicle formation.

research Morpho-Regulation of Ectodermal Organs

131 citations , March 2004 in “The American journal of pathology”

This study found that modulating BMP activity in transgenic mice affects the development and characteristics of several ectodermal organs, such as skin, hair, and claws, highlighting a stage-dependent influence on organogenesis.

research 1412 “Telescope model” for coordinated organ morphogenesis and stem cell formation

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study provided a dynamic 4D atlas showing the development process of mouse hair follicles through a telescope-like model, revealing new insights into the origin of hair follicle stem cells.

research Disrupted Ectodermal Organ Morphogenesis in Mice with a Conditional Histone Deacetylase 1, 2 Deletion in the Epidermis

32 citations , June 2013 in “Journal of Investigative Dermatology”

This study found that reducing HDAC1 activity in the skin of mice led to defects in hair follicle structure and pigmentation, highlighting HDAC's role in skin and hair maintenance.

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community Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect

126 upvotes 3 months ago

PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.

community New study: Vitamin D counteracts DHT in mice and in human hair organ culture and hair cells

126 upvotes 1 year ago

Vitamin D may counteract DHT and help with hair growth, as seen in mice and human hair cultures. Some users discuss using Vitamin D, magnesium, and other supplements for hair health, while others humorously note the success in mice.

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