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GlossaryCastration (Orchidectomy)

surgical removal of testicles in males

Castration, also known as neutering or orchiectomy, is the surgical removal of the testicles in males. This procedure is commonly performed on animals to prevent reproduction and reduce aggressive behavior, but it can also be done in humans for medical reasons such as hormone-related cancers.

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research Sub-Chronic Testosterone Treatment Increases the Levels of Epithelial Sodium Channel (ENaC)-α, β, and γ in the Kidney of Orchidectomized Adult Male Sprague–Dawley Rats

18 citations , June 2016 in “PeerJ”

Testosterone increases certain kidney protein levels, potentially raising blood pressure.

research Semen Cryopreservation in Testicular Cancer: Before or After Orchidectomy?

February 2026 in “Andrology”

Post-orchidectomy semen has better DNA integrity for fertility treatments.

research Hairy Pinnae After Orchiectomy and Chemotherapy for Testicular Cancer: Acquired Localized Hypertrichosis of the Ears

4 citations , January 2011 in “Dermatology”

A patient grew extra hair on their ears after treatment for testicular cancer, possibly due to hormonal changes or genetics.

research Alopecia X in German Spitz Responsive to Orchiectomy Associated with the Use of Melatonin: Case Report

January 2025 in “Seven Editora eBooks”

Orchiectomy and melatonin helped a German Spitz regrow some hair.

research Alopecia X in German Spitz Responsive to Orchiectomy Associated with the Use of Melatonin: Case Report

January 2025 in “Aracê.”

Orchiectomy and melatonin helped a German Spitz regrow hair lost due to alopecia X.

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community Hair loss treatment rabbit hole [OC]

in Satire 317 upvotes 3 years ago

Hair loss treatments, ranging from topical minoxidil and finasteride to taking hormones such as estradiol or nandrolone, as well as a controversial suggestion of an orchiectomy. A hair system is also mentioned as an alternative solution.

community So I was wondering what stack are we on boys? 🤔

in Satire 480 upvotes 3 years ago

Treatments for hair loss, including microneedling, finasteride, minoxidil, dutasteride, RU-58841, pyrilutamide, pumpkin seed oil, rosemary water, orchiectomy, and estrogen.

community Transfeminine and wondering if minoxidil is right for me

in Transgender 5 upvotes 7 months ago

The conversation discusses using minoxidil, finasteride, biotin, rosemary oil, and microneedling for hair regrowth, particularly around the temples. The user is seeking a permanent solution to improve hair density without ongoing intensive treatments.

community Dutasteride is not maintaining my hair. What are some other good options?

in Treatment 2 upvotes 5 months ago

The user is experiencing diffuse hair loss despite using finasteride and dutasteride and is considering adding minoxidil, microneedling, or RU58841. They are also thinking about increasing the dutasteride dose or opting for a hair transplant, while being cautious about side effects.

community Any growth (been taking iron supplements)

in Is this regrowth? 7 months ago

The conversation discusses hair loss treatments, focusing on iron supplements for low ferritin levels and considering finasteride and minoxidil if thinning persists. There is debate over starting with finasteride versus dutasteride, with some users advocating for dutasteride due to its potency, while others caution about potential side effects.

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