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research Role of Neurosteroid Allopregnanolone on Age-Related Differences in Exercise-Induced Hypoalgesia in Rats

4 citations , November 2018 in “Journal of pharmacological sciences”

Mild exercise reduces pain in older rats through a brain chemical, while intense exercise reduces pain in all rats through a different pain-blocking process.

research Trends in the Development of New Drugs for the Treatment of Benign Prostatic Hyperplasia

14 citations , November 2006 in “Current Medicinal Chemistry”

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

research Expression of Mu-Opiate Receptor in Human Epidermis and Keratinocytes

111 citations , August 1998 in “Journal of Investigative Dermatology”

μ-opiate receptors in skin cells may affect skin health and healing.

Persistent Escalation of Alcohol Consumption by Mice Exposed to Brief Episodes of Social Defeat Stress: Suppression by CRF-R1 Antagonism

research Persistent Escalation of Alcohol Consumption by Mice Exposed to Brief Episodes of Social Defeat Stress: Suppression by CRF-R1 Antagonism

38 citations , April 2018 in “Psychopharmacology/Psychopharmacologia”

Blocking CRF-R1 can reduce alcohol intake in stressed mice.

research Neuroendocrine Controls of Keratin Expression in Human Skin

December 2018 in “IntechOpen eBooks”

Neurohormones help control skin health and could treat skin disorders.

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community I cry every day, everything is very depressing

in Finasteride/Dutasteride 52 upvotes 11 months ago

A user is experiencing hair loss despite using dutasteride and oral minoxidil, feeling hopeless and considering a hair system. They are advised to try ketoconazole, seek a second opinion from a dermatologist, and consider treatments like finasteride, RU58841, and hair transplants.

community Horrible news, Stemson Therapeutics has shut down

in Technology 193 upvotes 1 year ago

Stemson Therapeutics has shut down, disappointing those seeking a hair loss cure. Current treatments like minoxidil, finasteride, and dutasteride are discussed, with some users experiencing side effects and exploring alternatives like PP405.

community Quitting kratom stopped my hairloss by 80%

in Research/Science 67 upvotes 1 year ago

Quitting kratom reduced hair loss by 80% for a 23-year-old male. Others discussed kratom's effects and potential side effects on hair health.

community Is it sufficient to block scalp DHT topically, or is it also necessary to reduce serum DHT? (My Question is Elaborated Below)

in Research/Science 17 upvotes 1 year ago

Topical finasteride can be as effective as oral finasteride for hair regrowth with fewer systemic side effects, but precise dosing is essential. Combining oral dutasteride with topical finasteride is not recommended due to dutasteride's stronger inhibition.

community Evolution theory: AGA is your body trying to reduce the risk of prostate cancer by exposing your scalp to more UV

in Research/Science 3 months ago

Androgenic alopecia (AGA) might have evolved to reduce prostate cancer risk by increasing UV exposure to the scalp, but this theory is debated. Treatments like minoxidil and finasteride are used for AGA, though the exact causes and evolutionary reasons for hair loss are unclear.

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