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This review discusses adverse effects of cosmetic products and procedures on the ocular surface, including mild discomfort to severe vision-threatening conditions, and reports no new clinical results.

In this survey study, dermatologists in the Aseer region of Saudi Arabia generally exhibited good knowledge of isotretinoin's ocular side effects like dry eye and contact lens intolerance, but their practices varied regarding patient education and management of these effects.

In this observational study of female undergraduate students, researchers found a significant correlation between the use of eyelash extensions and ocular side effects such as itching, lashes pulling out, and heavy eyelids, affecting 54% of participants during or after use.

This review synthesizes information on isotretinoin’s systemic toxicity, emphasizing that its adverse effects, including mucocutaneous, hepatic, and musculoskeletal reactions, primarily reflect its pharmacodynamic actions and are generally manageable with individualized dosing and monitoring, though its teratogenicity remains a significant safety concern.

In this retrospective study at Hiroshima University, methotrexate effectively controlled ocular inflammation in Japanese patients with non-infectious uveitis over 6 to 24 months, but a high incidence of adverse effects indicates careful monitoring and dose adjustments are important.