January 1990 in “Springer eBooks” Some chemicals can permanently or temporarily remove color from skin and hair, which can be distressing and is not well-regulated in cosmetics.
July 2025 in “Dermatology Practical & Conceptual” Topical eyedrops may cause eyelash whitening and skin lightening around the eyes.
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January 2000 in “Dermatology” This case report describes two patients who developed leucoderma on the scalp after using 2% minoxidil lotion, with repigmentation occurring after discontinuation.
November 2025 in “The Journal of Dermatology” This review summarizes recent pathological discoveries related to chemical leukoderma and chemical-induced vitiligo, especially focusing on rhododendrol, a chemical responsible for a significant outbreak affecting around 20,000 individuals in Japan and Asia.
October 2001 in “WORLD SCIENTIFIC eBooks” This compilation on contact and occupational dermatology in the Asia-Pacific region discusses various allergens and irritants without reporting new clinical findings.