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research Modification of testosterone levels with Piptadeniastrum africanum and Cordia plathytyrsa may influence metabolic parameters in Wistar rats

July 2022 in “Zenodo (CERN European Organization for Nuclear Research)”

In this animal study, methanolic extract of *Cordia plathytyrsa* increased testosterone synthesis in male rats but had limited effects on metabolic parameters, while *Piptadeniastrum africanum* raised triglycerides and both extracts did not cause oxidative stress.

Integrative Nutritional Mechanisms of Keyora Lycopene 23 in 1 Men's Multi-Vitamin in Erectile Dysfunction, Male Infertility, Prostatic Disorders, and Metabolic Dysregulation

research Integrative Nutritional Mechanisms of Keyora Lycopene 23 in 1 Man's Multi-Vitamin in Erectile Dysfunction, Male Infertility, Prostatic Disorders, and Metabolic Dysregulation

November 2025 in “Zenodo (CERN European Organization for Nuclear Research)”

This study found that the Keyora Lycopene 23 in 1 formulation may improve various aspects of male endocrine and reproductive health by targeting oxidative stress, nitric oxide deficiency, and hormonal imbalance.

research Integrative Nutritional Mechanisms of Keyora Lycopene 23 in 1 Man's Multi-Vitamin in Erectile Dysfunction, Male Infertility, Prostatic Disorders, and Metabolic Dysregulation

November 2025 in “Zenodo (CERN European Organization for Nuclear Research)”

In this study, the researchers introduced the Keyora Lycopene 23 in 1 formulation, demonstrating its potential to improve male endocrine and reproductive health by addressing oxidative stress, nitric oxide deficiency, androgen imbalance, and mitochondrial dysfunction through a comprehensive multi-nutrient approach.

Effect of Cuscuta Reflexa Extract in Mitigating Testosterone-Induced Benign Prostatic Hyperplasia in Rats: Targeting Inflammation and Oxidative Stress

research Effect of Cuscuta reflexa Extract in Mitigating Testosterone-Induced Benign Prostatic Hyperplasia in Rats: Targeting Inflammation and Oxidative Stress

April 2025 in “Al-Rafidain Journal of Medical Sciences ( ISSN 2789-3219 )”

In this study, researchers observed that Cuscuta reflexa extract mitigated inflammation and oxidative stress in testosterone-induced benign prostatic hypertrophy in Wistar rats, suggesting its potential as an adjunctive therapy for BPH.

research The Chronic Thermal Stress Model of Androgenetic Alopecia: A Unified Environmental–Vascular–Molecular Hypothesis

April 2026 in “Zenodo (CERN European Organization for Nuclear Research)”

This paper introduces a hypothesis that elevated DHT at puberty may increase cerebral heat output, creating chronic thermal stress linked to androgenetic alopecia, and suggests this could be tested with MR thermometry.

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Community Join

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community Can testosterone alone cause hair loss even after nuking DHT?

in Research/Science 26 upvotes 7 months ago

Testosterone can still cause hair loss even when DHT is blocked by dutasteride, especially if hair follicles are sensitive. Topical treatments like RU58841 or pyrilutamide may help, but their long-term effectiveness is uncertain compared to dutasteride.

community The most nuclear stack possible

45 upvotes 1 year ago

A user humorously suggests an extreme hair loss treatment regimen involving multiple medications and therapies, including Dutasteride, Minoxidil, RU58841, and others, claiming it would prevent hair loss but with potential side effects like gynecomastia. The conversation highlights concerns about safety, side effects, and the effectiveness of such a comprehensive approach.

community Wouldn’t this nuclear stack make it almost impossible to lose hair?

67 upvotes 1 year ago

The conversation discusses a hair loss treatment regimen involving dutasteride, pyrilutamide, oral minoxidil, and microneedling, with the aim of suppressing DHT and stimulating hair growth. Users debate the effectiveness and potential side effects of these treatments, noting that individual results may vary and that no treatment is foolproof.

community My hair loss makes no sense I can't stand it

30 upvotes 1 year ago

A user experienced severe hair loss after taking testosterone, despite using treatments like Dutasteride, RU58841, and Minoxidil. The user regrets taking testosterone, as it seems to have permanently increased sensitivity to DHT, accelerating hair loss.

community The homeless crackhead protocol

4487 upvotes 1 year ago

The conversation humorously suggests that drug use might be more effective for hair retention than traditional treatments like minoxidil or finasteride. It attributes full heads of hair in homeless individuals to lifestyle factors like reduced stress or hormonal changes.

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Experts

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Hair Loss Specialist
Dr. Fernando Testi, MD
Benissa, Comunitat Valenciana, Spain

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Dr. Fernando Testi, MD