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research MicroRNA-302 Increases Reprogramming Efficiency via Repression of NR2F2

123 citations , November 2012 in “Stem cells”

This study reports that miR-302 promotes pluripotency by inhibiting NR2F2 and indirectly regulating OCT4 in stem cells, enhancing reprogramming efficiency when added to traditional factors.

research Activation of Nrf2 in keratinocytes causes chloracne (MADISH)‐like skin disease in mice

81 citations , February 2014 in “EMBO molecular medicine”

This study found that prolonged Nrf2 activation in mouse keratinocytes led to enlarged sebaceous glands, hair loss, and cysts, suggesting a role for Nrf2 in conditions like MADISH.

research Oxidative Damage Control in a Human (Mini-) Organ: Nrf2 Activation Protects against Oxidative Stress-Induced Hair Growth Inhibition

58 citations , October 2016 in “Journal of Investigative Dermatology”

This study found that activating Nrf2 in human hair follicles significantly reduced oxidative stress, lipid peroxidation, and protected against hair growth inhibition, suggesting a protective role for Nrf2 against redox insult in this context.

research Oxidative stress management in the hair follicle: Could targeting NRF2 counter age‐related hair disorders and beyond?

30 citations , July 2017 in “BioEssays”

This review discusses the potential benefits of activating NRF2 for treating hair follicle disorders linked to oxidative stress and reports no new clinical results.

research Fernblock® Upregulates NRF2 Antioxidant Pathway and Protects Keratinocytes from PM_2.5-Induced Xenotoxic Stress

19 citations , April 2020 in “Oxidative Medicine and Cellular Longevity”

This study provides evidence that Fernblock® upregulates antioxidant pathways in cultured keratinocytes, potentially protecting against damage from fine pollutant particles.

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community Little hairs sprouting after 10, years of NRW 7

in Is this regrowth? 8 upvotes 6 months ago

A 35-year-old man with 10 years of hair loss at NRW7 started using topical Minoxidil and noticed some hair regrowth. He plans to continue with Minoxidil, add microneedling, and possibly try topical treatments like finasteride or dutasteride.

community Nicotinamide Riboside Experience

5 upvotes 4 years ago

Nicotinamide Riboside (NR) significantly reduced hair loss for the user. They found science.bio's NR to be effective, unlike other brands.

community I found the solution for the Minox dandruff problem

9 upvotes 5 years ago

A user found a solution for Minoxidil-induced dandruff by using a custom NRF 11.121 mixture from a local pharmacy, which includes ingredients like Isopropyl palmitate and Cremophor RH 40. This formulation prevents dryness and allows better penetration when using hair shaders.

community 40 days on topical fin+min + kx-826

24 upvotes 5 months ago

A user shared progress pictures after 40 days of using topical finasteride, minoxidil, and KX-826 following a hair transplant. They previously used Polaris NR-11, which contains finasteride and minoxidil, and experienced significant hair regrowth.

community 4 months into treatment, thoughts?

in Is this regrowth? 190 upvotes 1 year ago

The user is experiencing positive hair regrowth results after four months of using oral finasteride (1mg daily), oral minoxidil (5mg daily), Polaris NR02 shampoo, and ketoconazole 2% shampoo. They plan to continue the regimen and consider a hair transplant in the future, with no reported side effects from the current treatment.

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