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5 / 17 resultslearn Clascoterone
a novel topical treatment that inhibits DHT on androgen receptors
learn RU58841
a potent but unapproved and potentially problematic topical anti-androgen
learn PP405
mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials
learn Pyrilutamide
highly targeted anti-androgen that might have minimal systemic effects
Research
5 / 1000+ results
research Recent Advances in Thiasteroids Chemistry
New sulfur-containing steroid analogs show promise for more targeted medical treatments.
research Importance of Islet Intracrinology for Glucose-Stimulated Insulin Secretion in Males
Androgens and estrogens are crucial for insulin secretion in males.
research Androgen- and Estrogen-Secreting Adrenal Cancers
Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.
research Mechanism of Action of Herbs and Their Active Constituents Used in Hair Loss Treatment
Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.
research Glucocorticoid and Sex Hormone Receptors: Clinical Implications and Therapeutic Relevance
Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.
Community Join
5 / 115 resultscommunity PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance
The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.
community Got a microscope camera. Here’s the difference between healthy and miniaturized hair
A user who shared progress pictures of their scalp using a microscope camera, demonstrating the difference between healthy and miniaturized hair. Various explanations for the cause of this were discussed, such as DHT build-up in scalp sebum causing an autoimmune response leading to inflammation and eventual hair loss, with some suggesting a do-it-yourself treatment involving adding ascorbic acid powder to shampoo.
community Would Verteporfin be the true ‘cure’ as it could reverse a NW7 to a NW1?
Verteporfin might reverse severe hair loss but is still in early testing stages. It could be a future option for NW6-7, though expensive.
community [study analysis] Microdose of topical Finasteride for all the benefits and none of the sides?
Topical finasteride as a potential alternative to oral finasteride for reducing DHT levels on the scalp with fewer side effects, and other hair loss treatments such as minoxidil.
community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.
Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.