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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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research New Fluorogenic Probes for Neutral and Alkaline Ceramidases
New probes were created to effectively measure specific enzymes involved in fat metabolism, which could help develop new drugs.
research Alkaline Ceramidase 1 Protects Mice from Premature Hair Loss by Maintaining the Homeostasis of Hair Follicle Stem Cells
Alkaline Ceramidase 1 prevents early hair loss in mice by keeping hair follicle stem cells balanced.
research Structural and Functional Studies of L-PGDS and SMPDL3A Enzymes in Lipid Signaling Family
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
research Index
The document is a detailed medical reference on skin and genetic disorders.
research Enzymes
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
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5 / 86 resultscommunity Weed/THC effects on hair growth/hair loss, and vitality of organ-culture human follicle studies (research review)
Cannabis and THC may have mixed effects on hair, with some studies suggesting potential negative impacts on hair growth in isolated hair follicles, but these results are hard to apply to living humans. Treatments like minoxidil and finasteride are commonly used for hair loss, and the effects of cannabis might be neutral or vary based on individual factors.
community 24 years old, 6 month progress on once daily 1mg fin and twice daily topical minoxidil
A 24-year-old shared six months of progress using 1mg finasteride daily and topical minoxidil twice daily, reporting improved hairline and temples with no side effects. The user experienced initial shedding but noted significant regrowth and no erectile dysfunction issues.
community Blocking DHT helps slow down aging or increases it?
Blocking DHT may slow down aging and improve skin, with users reporting positive effects from finasteride. Minoxidil and RU58841 are also mentioned as treatments.
community A better treatment would be a localized 5ar inhibitor that breaks down when it enters blood or leaves hair follicle
The conversation discusses the need for a localized 5-alpha reductase inhibitor that only affects the scalp without systemic side effects, similar to pyrilutamide's approach. Current treatments like topical liposomal finasteride and dutasteride are mentioned, but concerns about their systemic effects and lack of research are highlighted.
community Topical minoxidil brand (and form of application) matters. You can be a hyper-responder to one product and a non-responder to another.
Different minoxidil formulations affect hair growth and side effects. Higher propylene glycol and pH levels improve effectiveness but can cause scalp irritation.