This review reports that hair follicles are dynamic neuro-immuno-endocrine organs with intrinsic signaling pathways, which play a crucial role in hair disorders like alopecia. It highlights emerging regenerative approaches targeting these pathways for hair restoration.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review reports that alopecia, particularly alopecia areata, significantly impacts mental health and quality of life through stress and immune mechanisms, with treatments like Janus kinase inhibitors showing promise for improving both hair regrowth and psychological well-being.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review found significant psychosocial impacts of alopecia, noting that those with alopecia, particularly alopecia areata, experience higher rates of depression and anxiety. The review also highlighted new treatments like Janus kinase inhibitors that improve both hair regrowth and quality of life.
January 2025 in “International Journal of Forest Animal and Fisheries Research” This review found that while elevated DHEA levels are observed in some women with PCOS, especially those with hyperandrogenism, inconsistencies across studies suggest that standardized measurement and analyses are needed to clarify DHEA's role as a biomarker and factor in PCOS pathophysiology.
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May 2009 in “Journal of Investigative Dermatology” This research highlights that psychological stress can adversely affect hair growth in mice, implicating potential pathways that may be relevant in understanding stress-induced hair growth inhibition in humans.