119 citations
,
January 2000 in “British Journal of Dermatology”
This study found that keratin expression patterns vary within nailunit structures, with the nail matrix uniquely expressing the acidic hair-type keratin Ha1.
55 citations
,
February 2013 in “The Anatomical Record”
This study found that the mouse nailunit structurally resembles the human nailunit, indicating it could be useful for researching nail diseases and biology.
10 citations
,
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”
This study revealed that BMP5 in onychofibroblasts may play a key role in the differentiation of nail matrix keratinocytes, highlighting transcriptional similarities between nail and hair structures.
This study reported that immunotherapy in cancer patients can lead to skin-related immune adverse events, such as rashes, pruritus, and vitiligo, affecting a substantial proportion of patients.
This report describes a unique benign neoplasm on the nailunit called onychoblastoma, which histologically resembles a trichoblastoma, marking the first documented case of this tumor type.
Chris's hair transplant looks better, but the hairline is criticized for being too straight and unnatural. Some recommend using finasteride and minoxidil for maintenance.
Minoxidil is highly toxic to pets, especially cats and dogs, even in small amounts. Many users have switched to oral minoxidil to prevent accidental exposure to their pets.
A user experienced side effects from finasteride and switched to using GHK-Cu for hairline improvement, noticing some positive changes after three months. They used a 2mg daily dose via subcutaneous injections and reported increased hair density and baby hairs, though results were not dramatic.
PP405 is a potential hair loss treatment that may activate dormant hair follicles, but there are concerns about its effectiveness, cost, and side effects. Users discuss treatments like minoxidil, finasteride, and RU58841, expressing skepticism about PP405's long-term success and accessibility.