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An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess

research An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess

27 citations , December 2013 in “Endocrinology”

This study established a mouse model for Cushing's syndrome due to a specific Crh mutation, which may help explore the effects of glucocorticoid excess and evaluate treatments for corticosteroid-induced osteoporosis.

research Corneodesmosomes and corneodesmosin: from the stratum corneum cohesion to the pathophysiology of genodermatoses

83 citations , May 2011 in “European Journal of Dermatology”

This review discusses the role of corneodesmosin in skin and hair follicle integrity, with mentions of its link to hypotrichosis simplex and peeling skin disease, and reports no new results.

research Bioactivity of Fractions and Pure Compounds from Jatropha cordata (Ortega) Müll. Arg. Bark Extracts

November 2023 in “Plants”

This study evaluated compounds from Jatropha cordata bark, finding that a sterol mixture and n-heptyl ferulate demonstrated notable anti-inflammatory activity in murine macrophage cells without toxicity, suggesting potential for treating chronic inflammation.

research Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation

27 citations , July 2017 in “Scientific Reports”

This study found that conditional knockout of N-WASP in keratinocytes of mice led to skin barrier defects, increased immune cell infiltration, and hyperproliferation of keratinocytes, indicating its crucial role in skin homeostasis.

research Characteristics of serum immunoglobulin G N-glycans in male patients with androgenetic alopecia

July 2025 in “Chinese Journal of Dermatology”

This study reported differences in serum IgG N-glycans between male patients with different types of androgenetic alopecia, suggesting that GP10 and GP22 may serve as biomarkers for assessing hair loss severity in male FPHL.

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Learn

3 / 801 results

learn Hair Transplant

How much does a hair transplant cost? Hair transplant costs typically range from $1,000 to $25,000 depending on various factors.

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Overview

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Community Join

5 / 362 results

community Do you Have Poor Posture? Maybe Contributing to Hair Loss , Esp Diffuse Thinning

in Research/Science 16 upvotes 3 weeks ago

Correcting posture may improve hair health by enhancing blood circulation and reducing side effects like bloating and sexual issues. The user has been using minoxidil and finasteride for two years with underwhelming results and is exploring posture correction as a potential aid.

community Let Me Sell You on NAC

17 upvotes 7 years ago

The conversation discusses using NAC (N-Acetyl Cysteine) alongside minoxidil and finasteride for hair loss, with some users noting potential hairline improvement and increased energy. The original poster reduced their finasteride dosage due to mental decline and anxiety, and while NAC's effects on hair are anecdotal, it is considered low-risk with other health benefits.

community Are carbohydrates needed for hair growth

26 upvotes 2 years ago

A 47-year-old male experienced significant hair loss after losing 37 kg in 6 months on a low-carb diet and started taking biotin, zinc, iron, selenium, and spectral dcn-n. Replies suggest that while carbs are not directly needed for hair growth, they help regulate hormones and nutrient absorption, and rapid weight loss can also contribute to hair loss.

community "DHT Itch" and onset Seborrheic Dermatitis

in Research/Science 76 upvotes 2 years ago

The post and conversation discuss the link between DHT (a hormone), scalp itchiness, and hair loss. Some users share their experiences and treatments, including the use of fluconazole, corticosteroids, and ketoconazole shampoo, with one user suspecting minoxidil as a potential cause of their symptoms.

community 75 days on Oral Min & Oral Fin Retrograde Alopecia

64 upvotes 4 months ago

A user shared their 75-day progress using oral minoxidil, finasteride, ketoconazole shampoo, and dermastamping for retrograde alopecia, reporting significant improvement and increased body hair without side effects. They also discussed quitting smoking and the potential correlation between early beard growth and male pattern baldness.

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