April 2019 in “Journal of Investigative Dermatology” This study in mice found that fractional photothermolysis can improve dermal scar formation by promoting slow, organized collagen regeneration with minimal myofibroblast activation.
July 2025 in “Pharmaceutics” This study found that Annexin A5 significantly reduced fibrosis and inflammation in both preventive and therapeutic contexts in a bleomycin-induced localized scleroderma mouse model, demonstrating its potential anti-fibrotic and anti-inflammatory effects for treating fibrotic diseases.
August 2024 in “Life Science Alliance” This study found that topical application of TGF-β mimic promoted enhanced wound healing and tissue regeneration in mice, suggesting its potential as a therapeutic option for improving wound healing.
29 citations
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September 2012 in “Birth Defects Research” This review discusses the developmental regulation of wound healing mechanisms in mammals, focusing on the role of the Wnt and TGF‐β signaling pathways, and reports no new clinical findings.
12 citations
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December 2021 in “Fundamental Research” This study found that (-)-blebbistatin significantly inhibited liver fibrosis in mouse models by reducing tissue stiffness and myofibroblast activation, indicating potential for developing broad-spectrum antifibrotic drugs.