research Differential Metabolic Adaptations Define Responses of Winner and Loser Oncogenic Mutant Stem Cells in Skin Epidermis In Vivo
Mutant stem cells adapt their metabolism differently to outcompete normal cells in the skin.
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5 / 1000+ resultsresearch KRASG12D Mutant Cells Are Outcompeted by Wild Type Neighbors in Adult Pancreas in an EPHA2-Dependent Manner
Normal cells outcompete and remove mutant cells in the pancreas with the help of the EphA2 receptor.
research Spreading of Isolated Ptch Mutant Basal Cell Carcinoma Precursors Is Physiologically Suppressed and Counteracts Tumor Formation in Mice
External factors can cause skin cancer cells that usually don't spread to grow and form tumors in mice.
research Live-Imaging the Interface Between Homeostasis and Cancer Initiation
Mutant cells in hair follicles are influenced by their location and interactions with surrounding cells.
research Correction of Hair Shaft Defects Through Allele-Specific Silencing of Mutant Krt75
Using special RNA to target a mutant gene fixed hair problems in mice.
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5 / 20 resultscommunity Is Elon on fin or dut? He made at least one transplant before
Elon Musk likely had at least two hair transplants and uses finasteride or dutasteride to maintain his hair. He may also use a hair system or prosthetic hair.
community Dutasteride: More Than a DHT Reducer – A Potential Androgen Receptor Inhibitor?
Dutasteride may inhibit androgen receptors in addition to reducing DHT, potentially explaining its effectiveness over finasteride for hair loss. Concerns about its impact on muscle growth are debated, with some suggesting no significant effects.
community What was your "fuck it, I'm starting Fin/Dut" moment?
People discussed starting hair loss treatments like finasteride, dutasteride, and minoxidil due to personal experiences or comments about their hair loss. Some reported positive results, while others mentioned side effects or switching treatments.
community Does Nuking Scalp DHT Theoretically Make Minoxidil Gains Permanent?
Minoxidil gains are not permanent without continued use, even with DHT suppression. Combining treatments like Dutasteride, Finasteride, and RU58841 may help maintain hair, but stopping Minoxidil typically results in hair loss.
community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)
There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.