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GlossaryMultipotent Stem Cells

can develop into multiple, but limited, cell types

Multipotent stem cells are a type of stem cell that can develop into multiple, but limited, cell types within a particular tissue or organ. For example, hematopoietic stem cells in the bone marrow can differentiate into various types of blood cells, but not into cells of other tissues like neurons or muscle cells. These cells are crucial for tissue repair and regeneration, making them a significant focus in medical research and therapies.

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research Defining the Impact of Beta-Catenin/Tcf Transactivation on Epithelial Stem Cells

384 citations, June 2005 in “Genes & development”

β-catenin is essential for stem cell activation and proliferation in hair follicles.

research Disruption of Smad4 in Mouse Epidermis Leads to Depletion of Follicle Stem Cells

43 citations, December 2008 in “Molecular biology of the cell”

Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.

research Stem Cells as a Target for the Delivery of Active Molecules to Skin by Topical Administration

2 citations, March 2020 in “International Journal of Molecular Sciences”

Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.

research Multipotent Nestin-Expressing Hair Follicle Stem Cells

37 citations, January 2009 in “The Journal of Dermatology”

Hair follicle stem cells can turn into various cell types and help repair nerves.

research Hair Follicle: A Novel Source of Multipotent Stem Cells for Tissue Engineering and Regenerative Medicine

65 citations, November 2012 in “Tissue Engineering Part B-reviews”

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

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community Microneedling and aloe vera to recruit stem cells.

in Chat 11 upvotes 10 months ago

Microneedling combined with aloe vera may stimulate dormant stem cells in hair loss areas. Minoxidil is also suggested for better results.