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Glossary Multipotent Stem Cells

can develop into multiple, but limited, cell types

Multipotent stem cells are a type of stem cell that can develop into multiple, but limited, cell types within a particular tissue or organ. For example, hematopoietic stem cells in the bone marrow can differentiate into various types of blood cells, but not into cells of other tissues like neurons or muscle cells. These cells are crucial for tissue repair and regeneration, making them a significant focus in medical research and therapies.

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research Isolation of a Novel Population of Multipotent Adult Stem Cells from Human Hair Follicles

344 citations , June 2006 in “American Journal Of Pathology”

Human hair follicles can provide stem cells for regenerative medicine.

research The multipotency of adult vibrissa follicle stem cells

8 citations , March 2009 in “Differentiation”

The study demonstrated that bulge stem cells from rat vibrissa follicles respond to adult dermal papilla signals, inducing hair bulb formation and regenerating hair structures in vivo.

research Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells

949 citations , January 2001 in “Cell”

This study demonstrated that multipotent stem cells in adult mice whisker follicles migrate to produce whisker growth, and that this process requires precise control of stem cell trafficking.

research The Hair Follicle Stem Cell as the Paradigm Multipotent Adult Stem Cell

1 citations , January 2008 in “Springer eBooks”

This study found that hair follicle stem cells are multipotent and can enhance nerve regeneration and function in mice, showing potential as an accessible source for treating peripheral nerve injuries.

research Tfap2b specifies an embryonic melanocyte stem cell that retains adult multi-fate potential

June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study discovered that the gene Tfap2b identifies a melanocyte stem cell population in zebrafish, essential for regenerating melanocytes with multi-fate potential into adult pigment cells.

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