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GlossaryMale Unpatterned Hair Loss (MUHH)

diffuse thinning of hair across the entire male scalp

Male Unpatterned Hair Loss (MUHH) refers to a type of hair loss in men that does not follow the typical patterns seen in male pattern baldness, such as receding hairlines or balding at the crown. Instead, it involves a more diffuse thinning of hair across the entire scalp. This condition can be more challenging to diagnose and treat because it doesn't exhibit the characteristic patterns of androgenetic alopecia.

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A Newly Identified Missense Mutation of the HR Gene Is Associated with a Novel, Unusual Phenotype of Marie Unna Hereditary Hypotrichosis 1 Including Limb Deformities

research A Newly Identified Missense Mutation of the HR Gene Is Associated with a Novel, Unusual Phenotype of Marie Unna Hereditary Hypotrichosis 1 Including Limb Deformities

6 citations, May 2012 in “Archives of Dermatological Research”

A new mutation in the HR gene is linked to a rare form of hair loss with limb deformities.

research Hair Disorders

November 2019 in “Harper's Textbook of Pediatric Dermatology”

Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.

Significant Hair Regrowth With 5% Topical Minoxidil in a Child With Marie Unna Hereditary Hypotrichosis Caused by a Recurrent HRURF Variant

research Significant Hair Regrowth With 5% Topical Minoxidil in a Child With Marie Unna Hereditary Hypotrichosis Caused by a Recurrent HRURF Variant

August 2025 in “Journal of Cosmetic Dermatology”

5% topical minoxidil can significantly improve hair growth in children with Marie Unna hereditary hypotrichosis.

research Hairless And The Polyamine Putrescine Form A Negative Regulatory Loop In The Epidermis

10 citations, August 2013 in “Experimental Dermatology”

Hairless protein and putrescine regulate each other, affecting hair growth and skin balance.

research The Stem Cell Quiescence and Niche Signaling Is Disturbed in the Hair Follicle of the Hairpoor Mouse, an MUHH Model Mouse

October 2021 in “Research Square (Research Square)”

Hair follicle stem cells in hairpoor mice are disrupted, causing hair loss.

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community Proof that finasteride messes with neurosteroids

in Research/Science 230 upvotes 1 year ago

Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

community 28M hair transplant results, 6 months later. 3633 grafts via FUE

in Transplants 478 upvotes 4 years ago

28M shares hair transplant results 6 months after 3633 grafts via FUE by Dr. Rahal in Ottawa, costing ~$24k CAD. Users discuss the impressive results, procedure experience, and cost breakdown.