December 2024 in “Medicina (Ribeirão Preto)” This study found that 83% of acne patients treated with isotretinoin experienced adverse reactions, with the number of reactions related to treatment duration rather than sex, age, or dosage.
16 citations
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October 2014 in “Journal of the American Academy of Dermatology” This study found that oral retinoid therapy may provide clinical improvement in a small percentage of patients with treatment-resistant lichen planopilaris, although it is not commonly used as a first-line treatment.
June 2020 in “International Journal of Research in Dermatology” This study assessed clinical patterns of skin and mucosal symptoms in postmenopausal women, finding that a significant number experienced conditions like atrophic vaginitis, oral complaints, and hair loss, often without realizing their menopausal link.
October 2025 in “Journal of the Endocrine Society” This research review observed that topical hormone replacement therapy, particularly estradiol and estradiol-testosterone combinations, significantly increased Type I and III collagen synthesis in the skin of postmenopausal women, suggesting benefits against collagen loss-related skin aging effects such as reduced elasticity and increased dryness.
14 citations
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April 2022 in “Climacteric” This review discusses the impact of HRT on menopausal skin and hair symptoms and argues that potential benefits should be part of informed decision-making for managing menopause.