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GlossaryMelatonin Receptor 2 (MT2)

protein that binds melatonin to regulate sleep-wake cycles

Melatonin Receptor 2 (MT2) is a protein found in the body that binds to melatonin, a hormone that regulates sleep-wake cycles. This receptor plays a crucial role in various physiological processes, including circadian rhythm regulation and potentially influencing mood and immune function. Understanding MT2 is important for developing treatments for sleep disorders and other conditions related to the body's internal clock.

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research Melatonin Membrane Receptors in Peripheral Tissues: Distribution and Functions

506 citations , January 2012 in “Molecular and Cellular Endocrinology”

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

research Melatonin in the Skin: Synthesis, Metabolism, and Functions

252 citations , January 2008 in “Trends in Endocrinology and Metabolism”

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

The Role of Melatonin in Neuroectodermal-Mesodermal Interactions: The Hair Follicle Synthesizes Melatonin and Expresses Functional Melatonin Receptors

research The Role of Melatonin in Neuroectodermal-Mesodermal Interactions: The Hair Follicle Synthesizes Melatonin and Expresses Functional Melatonin Receptors

122 citations , July 2005 in “The FASEB journal”

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

research Melatonin and the Hair Follicle

109 citations , October 2007 in “Journal of pineal research”

Melatonin helps regulate hair growth and protects the hair follicle from stress.

research Expression and Functional Relevance of Melatonin Receptors in Hair Follicle Biology

9 citations , January 2005 in “Experimental dermatology”

Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.

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community Thoughts of this sub on Melatonin?

in Research/Science 3 upvotes 8 months ago

Melatonin, gingko biloba, and biotin are effective for treating hair loss with good tolerability. Alternatives like dutasteride, minoxidil, and other peptides are also discussed.

community Hairline itch when hairline’s receding

in Chat 80 upvotes 1 week ago

Hair loss treatments like finasteride, dutasteride, minoxidil, and RU58841. Users discuss "DHT itch" at receding hairlines and suggest using dutasteride or ketoconazole shampoo for relief.

community How do you guys deal with lower libido?

in Finasteride/Dutasteride 22 upvotes 4 years ago

A user discusses dealing with lower libido caused by finasteride, considering using ED meds but unsure due to age. Replies suggest natural libido fluctuations, holistic approaches, and managing anxiety.

community Finasteride and “anti-aging” effects

in Treatment 218 upvotes 1 month ago

Finasteride may help users look younger by suppressing DHT, affecting skin and hair. Users also emphasize skincare, sunscreen, and lifestyle for maintaining a youthful appearance.

community 23M Couldn’t go bald for fear of my Girlfriend leaving me.

in Is this regrowth? 1094 upvotes 3 months ago

A 23-year-old man uses a topical spray with minoxidil, finasteride, and tretinoin for hair loss, experiencing improved hair growth but occasional heart palpitations. He worries his girlfriend might leave him if he goes bald, but commenters advise that if she would leave over hair loss, she isn't worth it.

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