research LncRNA MSTRG.14227.1 regulates the morphogenesis of secondary hair follicles in Inner Mongolia cashmere goats via targeting ADAMTS3 by sponging chi-miR-433
This study investigates the role of lncRNA MSTRG.14227.1 in the development of secondary hair follicles in Inner Mongolia cashmere goats. The research identifies that this lncRNA inhibits the proliferation and migration of dermal fibroblasts, impacting hair follicle morphogenesis. It functions by sponging chi-miR-433, which in turn affects the expression of the target gene ADAMTS3. The findings suggest that lncRNA MSTRG.14227.1 plays a significant role in inhibiting the morphogenesis of secondary hair follicles via the chi-miR-433/ADAMTS3 signaling axis, which could have implications for improving cashmere yield and quality.
