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      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

      learn Spironolactone

      powerful topical and oral anti-androgen used mostly by women

    Research

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      community My Estradiol Level on Finasteride

      in Research/Science  18 upvotes 4 months ago
      Finasteride has no effect on the user's estradiol levels, and body fat may influence aromatization. The user is on testosterone replacement therapy and uses everyday injections to manage high RBC count, with plans to measure DHT, DHEA-S, and pregnenolone levels.

      community I think this is my stop, gentlepeople. So long and thanks for all the data 👋

      in Transgender  2253 upvotes 3 months ago
      A user shared their successful experience with hair regrowth and transitioning from male to female using minoxidil, finasteride, Nutrafol, microneedling, and hormone replacement therapy (HRT). They expressed gratitude for the results and encouraged others to explore treatments that align with their personal goals.

      community 2 years on treatment (stack update)

      in Progress Pictures  464 upvotes 7 months ago
      A user shared their hair regrowth progress using Dutasteride, topical Minoxidil, Spironolactone, and Estradiol Valerate injections as part of hormone replacement therapy for transitioning. They experienced significant hair improvement and personal satisfaction but caution against this approach for non-transitioning individuals due to irreversible changes.

      community Being Safe on Oral Minoxidil: tl;dr on the literature.

      in Research/Science  51 upvotes 9 months ago
      Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.