research Structural changes in trichocyte keratin intermediate filaments during keratinization
Keratin structure changes during keratinization, but the exact model remains uncertain.
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research ATOMISTIC CHARACTERIZATION OF HEALTHY AND DAMAGED HAIR SURFACES: A MOLECULAR DYNAMICS STUDY OF FATTY ACIDS ON PROTEIN LAYER
This study's simulations suggest that replenishing free 18‐MEA could restore damaged hair surface properties, highlighting the importance of optimal fatty acid spacing for maintaining hair integrity.
research Direct evidence supporting the existence of a helical dislocation in protofilament packing in the intermediate filaments of oxidized trichocyte keratin
Oxidized trichocyte keratin has a helical dislocation in its structure.
research Synthesis, Crystal Structure and Supramolecular Features of Novel 2,4-Diaminopyrimidine Salts
This study characterized the crystal structures and supramolecular architectures of new salts made from 2,4-diaminopyrimidine and different dicarboxylic acids, revealing subtle differences in crystal packing and hydrogen-bonding patterns, particularly influenced by sulfur atom interactions, through Hirshfeld analysis and enrichment ratios.
research Crystal Structure of 3-Oxo-4-Aza-5-Alpha-Androstone-17 β-Tert-Butyl Carboxamide with an O···H–(C, N) Acceptor Four-Center Hydrogen Bond
This study reports the crystal structure and geometric parameters of a modified Finasteride derivative, highlighting significant differences in dihedral angles compared to its solvated analog and computational models.
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5 / 640 resultscommunity New topical finasteride approved to hit the shelf very soon in France
A new topical finasteride has been approved in France, providing an alternative to oral finasteride with potentially fewer side effects. Users discuss the pros and cons of topical versus oral treatments, with some opting to create their own solutions to save money.
community How is there still no consensus on Topical Dutasteride in 2024?
The conversation expresses frustration over the lack of clear evidence regarding the effectiveness and systemic impact of topical Dutasteride for hair loss treatment, despite years of discussion. People are criticized for not conducting proper research and for providing contradictory anecdotal claims.
community Say this new supposed miracle drug “PP405” does actually cure baldness, how will that affect people with hair transplants?
PP405 may reactivate dormant hair follicles but won't replace hair transplants or resurrect dead follicles. Its effectiveness, cost, and impact compared to treatments like minoxidil and finasteride are uncertain.
community What can be the real reason of Finasteride SE ?
Finasteride can cause side effects like erectile dysfunction and decreased libido, possibly due to increased estradiol from testosterone aromatization, especially in those with higher body fat. Side effects vary widely and may also be influenced by genetic factors or neurosteroid inhibition.
community Is this much of a hair shed a good sign after starting nuclear stack? Ok
The conversation discusses hair shedding after starting a treatment regimen including topical dutasteride, RU58841, minoxidil, and keto shampoo. Shedding is considered normal, and users suggest adjustments like increasing dutasteride dosage or using oral medications for better results.
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