19 citations
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January 2018 in “BioMed Research International” miR-195-5p reduces hair growth ability in cells by blocking a specific growth signal.
13 citations
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September 2018 in “Scientific Reports” The research found that a complex gene network, controlled by microRNAs, is important for hair growth in cashmere goats.
July 2025 in “Preprints.org” This study on alopecia areata (AA) identifies distinct plasma miRNA profiles that could aid in diagnosis and therapy. Involving 140 participants, including 50 AA patients, the research found 19 miRNAs significantly downregulated in AA, with nine validated for both mild and severe forms. Key miRNAs with high classification potential were miR-130b-3p, miR-296-5p, miR-424-5p, and miR-195-5p. Machine learning demonstrated strong predictive accuracy for AA (AUC = 0.94). Pathway analysis revealed immune-related pathways, such as Interferon-gamma and JAK/STAT, as significant. Kinase inhibitors were identified as promising therapeutic targets. These findings are exploratory and require further validation.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Dermal papilla cell-derived exosomes can help stem cells grow hair.
March 2024 in “Research Square (Research Square)” The TT genotype of a specific SNP in sheep is linked to better wool quality.