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This study found no significant association between mineralocorticoid receptor antagonist therapy and mortality in patients with SARS-CoV-2 infection.

This study found that using mineralocorticoid receptor antagonists with glucocorticoid therapy improved wound healing in diabetic animals by enhancing keratinocyte proliferation and epithelialization.

This study found that inhibiting mineralocorticoid receptor signaling in female human hair follicles may promote hair growth by extending the anagen phase and encouraging keratinocyte proliferation.

This study conducted a large-scale comparison using FAERS data to assess the post-marketing safety profiles of spironolactone, eplerenone, and finerenone, finding unique adverse event patterns for each drug and highlighting the need for personalized safety monitoring and further investigation in other pharmacovigilance databases.

This study observed that in vitro exposure to dihydrotestosterone worsened COVID-19 spike protein-induced endothelial injury, while spironolactone showed potential in reducing this effect, suggesting a rationale for further evaluation in treating COVID-19.