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GlossaryTissue Sectioning (Microtomy)

process of cutting thin tissue slices for microscopic examination

Tissue sectioning, also known as microtomy, is the process of cutting thin slices of biological tissue for examination under a microscope. This technique is crucial for studying the detailed structure of tissues, diagnosing diseases, and conducting research. The thin sections, typically only a few micrometers thick, allow for the visualization of cellular and subcellular components when stained and viewed under a microscope.

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research Histopathologic Evaluation of Alopecias

90 citations, June 2006 in “The American Journal of Dermatopathology”

The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.

research Topical Delivery of Protein and Peptide Using Novel Cell Penetrating Peptide IMT-P8

61 citations, May 2016 in “Scientific reports”

The peptide IMT-P8 can effectively deliver proteins into the skin and cells for potential skin treatments.

research Development and Characterization of Minoxidil-Loaded Liposomal System for Delivery to Pilosebaceous Units

34 citations, March 2004 in “Journal of Liposome Research”

Minoxidil-loaded liposomes effectively deliver to hair follicles, potentially improving hair growth and treating alopecia.

research Effect of Citrullus Colocynthis Schrad Fruits on Testosterone-Induced Alopecia

31 citations, September 2009 in “Natural Product Research”

Citrullus colocynthis fruit extract may effectively treat testosterone-related hair loss, similar to finasteride.

research Effect of Tectona Grandis Linn. Seeds on Hair Growth Activity of Albino Mice

19 citations, January 2010 in “International Journal of Ayurveda Research”

Tectona grandis Linn. seeds extract improved hair growth in mice better than minoxidil.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Painkillers May Block Minoxidil

in Research/Science 14 upvotes 1 month ago

Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

community Switched from finasteride to dutasteride - 2 month update

in Finasteride/Dutasteride 6 upvotes 1 year ago

The user switched from finasteride to dutasteride for hair loss treatment, but experienced increased libido, itchy scalp, and accelerated hair loss. Another user suggested that genetic variations might cause dutasteride to be less effective and recommended checking for specific genetic markers.