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GlossaryTissue Sectioning (Microtomy)

process of cutting thin tissue slices for microscopic examination

Tissue sectioning, also known as microtomy, is the process of cutting thin slices of biological tissue for examination under a microscope. This technique is crucial for studying the detailed structure of tissues, diagnosing diseases, and conducting research. The thin sections, typically only a few micrometers thick, allow for the visualization of cellular and subcellular components when stained and viewed under a microscope.

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Phospholipid-Polymer Hybrid Nanoparticle-Mediated Transfollicular Delivery of Quercetin: Prospective Implementation for the Treatment of Androgenic Alopecia

research Phospholipid-Polymer Hybrid Nanoparticle-Mediated Transfollicular Delivery of Quercetin: Prospective Implementation for the Treatment of Androgenic Alopecia

18 citations , August 2019 in “Drug Development and Industrial Pharmacy”

Quercetin-loaded nanoparticles can penetrate skin, minimize hair loss, and promote hair regrowth, showing slightly better results than a marketed product.

research Effect of Tectona Grandis Linn. Seeds on Hair Growth Activity of Albino Mice

19 citations , January 2010 in “International Journal of Ayurveda Research”

Tectona grandis Linn. seeds extract improved hair growth in mice better than minoxidil.

research Development and Characterization of Minoxidil-Loaded Liposomal System for Delivery to Pilosebaceous Units

34 citations , March 2004 in “Journal of Liposome Research”

Minoxidil-loaded liposomes effectively deliver to hair follicles, potentially improving hair growth and treating alopecia.

research Effect of Citrullus Colocynthis on Hair Growth in Albino Rats

18 citations , January 2007 in “Pharmaceutical Biology”

Citrullus colocynthis extract is effective for hair growth, comparable to minoxidil.

research Techniques for the Discovery and Evaluation of Drugs Against Alopecia

5 citations , February 2011 in “Expert Opinion on Drug Discovery”

We need better treatments for hair loss, and while test-tube methods are helpful, they can't fully replace animal tests for evaluating new hair growth treatments.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 6 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Switched from finasteride to dutasteride - 2 month update

in Finasteride/Dutasteride 6 upvotes 2 years ago

The user switched from finasteride to dutasteride for hair loss treatment, but experienced increased libido, itchy scalp, and accelerated hair loss. Another user suggested that genetic variations might cause dutasteride to be less effective and recommended checking for specific genetic markers.

community Painkillers May Block Minoxidil

in Research/Science 13 upvotes 1 year ago

Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.