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Glossary Microdissection

precise technique to isolate specific cells under a microscope

Microdissection is a precise laboratory technique used to isolate specific cells or tissues from a larger sample under a microscope. This method is particularly useful in research and medical diagnostics, allowing scientists to study the genetic and molecular characteristics of individual cells, which can be crucial for understanding diseases like cancer or for hair follicle analysis in cases of alopecia.

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Research

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research Isolating Dermal Papilla Cells from Human Hair Follicles Using Microdissection and Enzyme Digestion

6 citations , January 2020 in “Methods in molecular biology”

This study outlines a method for isolating dermal papilla cells from human hair follicles, which may help overcome challenges in studying their role in hair growth.

research Laser microdissection and DNA typing of cells from single hair follicles

45 citations , December 2004 in “Forensic Science International”

This study reports that using laser microdissection to isolate telogen hair follicles significantly improves DNA extraction efficiency for STR typing, reducing contamination from keratin.

research Laser Capture Microdissection Reveals Transcriptional Abnormalities in Alopecia Areata before, during, and after Active Hair Loss

16 citations , December 2015 in “Journal of Investigative Dermatology”

This study found significant gene expression abnormalities in hair follicles affected by alopecia areata, suggesting persistent changes that may predispose to future relapses even after hair regrowth.

research Folliculotropic mycosis fungoides with central nervous system involvement: Demonstration of tumor clonality in intrafollicular T cells using laser capture microdissection

14 citations , February 2003 in “Journal of the American Academy of Dermatology”

This case report describes the first use of laser capture microdissection to confirm that atypical lymphocytes in a folliculotropic mycosis fungoides case involving the central nervous system were part of the same tumor clone.

research Laser capture microdissection as a method for investigating the human hair follicle microbiome reveals region-specific differences in the bacteriome profile

8 citations , March 2023 in “BMC Research Notes”

This pilot study explored a new method using laser-capture microdissection and 16S rRNA gene sequencing to analyze the human scalp hair follicle microbiome more accurately, revealing region-specific variations in microbial diversity and abundance.

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Community Join

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community 4 Month Progress (Min/Fin Oral, Micro-needling + Rosemary Oil every 4 days)

in Progress Pictures 736 upvotes 1 year ago

The user experienced significant hair regrowth over four months using oral finasteride, oral minoxidil, micro-needling, and rosemary oil. They reported no side effects and emphasized the importance of continuing the treatment to maintain results.

community 6 month update fin, min, micro-needle

in Progress Pictures 436 upvotes 1 year ago

The user experienced significant hair regrowth and improved hair quality after six months of using oral minoxidil, finasteride, and micro-needling. They reported increased libido initially but no other side effects, and they plan to continue the treatment.

community Holding the line with no meds.

49 upvotes 1 year ago

A 34-year-old man is using natural methods like rosemary and peppermint oil, micro-needling, and low-level laser therapy to manage hair thinning, avoiding medications like minoxidil and finasteride. Despite minimal visible progress, he values the non-medicated approach and remains consistent with his routine.

community My donor hair is still red after a year and a half.

58 upvotes 2 months ago

The conversation is about a user experiencing redness and tingling in the donor area after a hair transplant, with suggestions to use treatments like dutasteride and minoxidil. Other users recommend consulting a doctor, considering scalp micro pigmentation, or using body hair for future transplants.

community 6 Months in. Stick with it Fin? Or switch to Dut?

in Progress Pictures 53 upvotes 1 year ago

A 36-year-old man has been using oral finasteride and minoxidil for six months and is considering switching to dutasteride due to concerns about shedding and lack of response. Users suggest continuing with finasteride, trying micro-needling, or cautiously adding dutasteride while monitoring for side effects.

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