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This study found that diphencyprone showed a significant clinical response for treating alopecia areata, while tacrolimus was not effective.

Farudodstat may effectively treat alopecia areata without harming hair follicles.

Farudodstat may help treat alopecia areata by protecting hair follicles.

This study found that in an ex vivo model simulating alopecia areata, the DHODH inhibitor farudodstat reduced T-cell proliferation and MHC protein expression in hair follicles, suggesting it may protect against immune privilege collapse without cytotoxic effects.

This study indicates that CD4 protein may have a functional role in basal cell-like keratinocytes through TCR/CD3-independent signaling, affecting their proliferation, differentiation, and migration.