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research Clinical-Exome Sequencing Unveils the Genetic Landscape of Polycystic Ovarian Syndrome (PCOS) Focusing on Lean and Obese Phenotypes: Implications for Cost-Effective Diagnosis and Personalized Treatment
This study found that among young women in West Bengal, India, co-occurring PCOS and related conditions like estrogen resistance and leptin receptor insufficiency are common, with notable genetic variations identified, including impairments in leptin signaling and insulin resistance.
research Immune-Mediated Diseases of the Central Nervous System
This article discusses the diagnostic and therapeutic approach for immune-mediated central nervous system diseases but reports no new clinical findings.
research Biochemistry of Vitamin B: Metabolic Regulations, Deficiency Disorders and Emerging Therapeutic Strategies
This research highlights the crucial roles of B vitamins in metabolism, neurological processes, and DNA functions, and describes emerging therapies that enhance vitamin absorption and therapeutic potential.
research Clinical-exome sequencing unveils the genetic landscape of polycystic ovarian syndrome (PCOS) focusing on lean and obese phenotypes: implications for cost-effective diagnosis and personalized treatment
In this study using data from young women in West Bengal, India, the researchers identified that leptin signaling impairment, insulin resistance, and specific gene mutations significantly contribute to PCOS, with obesity commonly manifesting in affected individuals.
research Maternal nutrition at conception modulates DNA methylation of human metastable epialleles
This study found that the maternal nutritional status during early pregnancy significantly influenced epigenetic changes in offspring, as maternal diet altered DNA methylation at human metastable epialleles.
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