217 citations
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February 2009 in “The FASEB Journal” This study found that hydrogen peroxide accumulation and reduced methionine sulfoxide repair play a significant role in the oxidative damage linked to senile hair graying.
17 citations
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October 2010 in “Pigment cell & melanoma research” This article reviews the impact of H2O2-redox homeostasis on hair follicle pigmentation via tyrosinase and associated mechanisms, discussing primarily findings from murine models without providing new clinical results for humans.
June 2009 in “Pigment Cell & Melanoma Research” This review explores the role of oxidative stress and stem cell decline in hair graying, suggesting potential areas for future research but reports no new findings.
49 citations
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October 2017 in “Nutrients” This study observed that the ethyl acetate extract of Equisetum debile showed high activity against 5α-reductase and lipid peroxidation with no cytotoxicity on dermal papilla cells.
3 citations
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April 2021 in “Journal of Medicinal Chemistry” This study suggests that finasteride may inhibit the enzyme PNMT, potentially contributing to its sexual and psychological side effects.