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      research Bioavailability File: Bicalutamide

      August 2025 in “Fabad Journal of Pharmaceutical Sciences”
      This review highlights that bicalutamide, a non-steroidal antiandrogen used in prostate cancer treatment, is mainly effective through its (R)-enantiomer and emphasizes the need to monitor its adverse effects despite its targeted antiandrogenic action.

      research Review on Tridax Procumbens

      September 2024 in “International Journal For Multidisciplinary Research”
      This study highlights the significant pharmacological potential of Tridax procumbens, a plant with various therapeutic properties such as liver protection, immune modulation, and wound healing, though it notes that more research is needed to identify its active compounds and mechanisms for drug discovery.

      research Resident macrophages of the lung and liver: The guardians of our tissues

      4 citations , November 2022 in “Frontiers in Immunology”
      This review discusses the roles of resident macrophages in the liver and lung, emphasizing their unique contributions to maintaining tissue homeostasis and the interface between circulation and external environments, but reports no new findings.

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      community Attention Finasteride / Dutasteride and Your liver

       374 upvotes 1 year ago
      Finasteride may cause elevated liver enzymes, potentially leading to liver issues, though this is rare. Users should monitor liver function and consider topical alternatives if liver sensitivity occurs.
      Can liver problems be associated with response to the oral minoxidil?

      community Can liver problems be associated with response to the oral minoxidil?

      in Research  147 upvotes 8 months ago
      Liver problems may reduce the effectiveness of oral minoxidil due to impaired SULT1A1 enzyme activity, which is crucial for converting minoxidil to its active form. This reduction in enzyme function can significantly decrease the drug's effectiveness in promoting hair growth.

      community Being Safe on Oral Minoxidil: tl;dr on the literature.

       51 upvotes 1 year ago
      Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

      community Thoughts about ORAL ketoconazole? (pills)

      8 months ago
      Oral ketoconazole is discussed as a potential hair loss treatment, but it poses significant health risks like liver damage and adrenal insufficiency. Users suggest safer alternatives like topical anti-androgens or spironolactone, emphasizing the importance of consulting a specialist.

    Learn

    2 / 4 results

      learn Dutasteride

      5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride

      learn RU58841

      Experimental topical anti-androgen sold as a research chemical