April 2018 in “Journal of Investigative Dermatology” This study found that Mentha suaveolens aqueous extract activated Nrf-2 and increased detoxifying enzyme expression in keratinocytes, providing protection against oxidative stress without cytotoxicity.
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April 2018 in “Journal of Investigative Dermatology” In this study, OEA was found to significantly enhance sebaceous lipogenesis and potentially reduce inflammation in human sebocytes, suggesting it as a promising candidate for treating skin dryness.
April 2018 in “Journal of Investigative Dermatology” This study found that claudins CLDN1 and CLDN3 are crucial for maintaining proper hair follicle structure in mice, and their dysregulation may lead to telogen hair loss.
April 2018 in “Journal of Investigative Dermatology” This study found that acne lesions and nonlesional skin in mild-to-moderate acne patients showed significant Th17-skewing and increased antimicrobials, suggesting systemic targets like IL-17/IL-23/IL-36 could be therapeutic.
April 2018 in “Journal of Investigative Dermatology” This study found that terminally differentiated effector memory Vδ1T-cells and their cytotoxic activation markers were elevated in alopecia areata patients, suggesting these cells may contribute to its early pathogenesis.