February 2025 in “Clinical Cosmetic and Investigational Dermatology” This study used Mendelian randomization to explore associations between 1400 blood metabolites and female-pattern hair loss, finding 23 metabolites and 4 metabolic ratios linked to the condition, while identifying fructose/mannose metabolism as a significant pathway.
August 2025 in “Nutrients” This Mendelian randomization study found that specific dietary patterns, such as consuming antioxidant-rich foods like melon and tea, may have protective effects against hair loss, while processed carbohydrates, alcohol, and certain dairy products could increase the risk of androgenetic alopecia and alopecia areata.
29 citations
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October 2020 in “eLife” This study using Mendelian randomization in UK Biobank data suggests that lifelong increased free testosterone may have mixed effects, including increased bone density and prostate cancer risk, warranting well-powered trials to address uncertainties.
2 citations
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April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This article discusses the MendelVar webserver, which integrates Mendelian disease data with GWAS findings to prioritize candidate genes for complex traits and reports no new experimental results.
October 2025 in “Skin Research and Technology” The article's findings are unreliable and have been retracted.