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Did you mean Melanocortin 1 Receptor?

GlossaryMelanocortin 1 Receptor

regulates melanin production, affecting hair and skin color

The Melanocortin 1 Receptor (MC1R) is a protein found on the surface of melanocytes, the cells responsible for producing melanin, the pigment that gives skin, hair, and eyes their color. Variations in the MC1R gene can influence hair color, skin tone, and susceptibility to UV radiation, and are also associated with red hair and fair skin.

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research Receptors in Trichology: Hot Spots for Hair Regeneration

January 2013 in “International journal of trichology”

Vitamin D3 and its receptor are important for hair growth, and understanding receptors could help treat hair graying and skin cancer.

research Down-Regulation of Melanocortin Receptor Signaling Mediated by the Amino Terminus of Agouti Protein in Xenopus Melanophores

43 citations, May 1999 in “Journal of Biological Chemistry”

Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.

research Montagna Symposium 2013: Light and Skin - How Light Sustains, Damages, Treats, Images, and Modifies Skin Biology

1 citations, July 2014 in “The journal of investigative dermatology/Journal of investigative dermatology”

Light affects skin health, aging, and cancer risk, and new light-based treatments and imaging are promising for skin care.

research Efficacy of an Agonist of α-MSH, the Palmitoyl Tetrapeptide-20, in Hair Pigmentation

12 citations, September 2018 in “International Journal of Cosmetic Science”

Palmitoyl tetrapeptide-20 may help reduce hair greying and increase melanin production.

research EdnrB Governs Regenerative Response of Melanocyte Stem Cells by Crosstalk with Wnt Signaling

59 citations, April 2016 in “Cell Reports”

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

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