21 citations
,
May 2016 in “Experimental and Therapeutic Medicine” In this study, the researchers observed that MMP-2 and MMP-9 significantly fluctuated with the hair growth cycle in mice, suggesting their important role in hair development.
9 citations
,
August 2005 in “Archives of Dermatological Research” Scalp dermal papilla and fibrous sheath cells have different MMP expression than scalp dermal fibroblasts.
57 citations
,
March 2018 in “International Journal of Molecular Sciences” This review highlights recent advances in understanding how the extracellular matrix regulates epidermal stem cell fate, emphasizing the importance of the hair follicle stem cell niche, but reports no new empirical findings.
8 citations
,
June 2022 in “Frontiers in bioengineering and biotechnology” This study found that a collagen patch made with fibroblast-derived extracellular matrix (fdECM) extracted from human lung fibroblasts enhanced wound healing by promoting wound contraction, angiogenesis, and skin remodeling in full-thickness skin wound models, including those with diabetic ulcers.
20 citations
,
September 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that MMP-9 plays a significant role in extracellular matrix remodeling during hair canal formation in mice, as indicated by delayed hair shaft emergence and hair canal development in MMP-9 knockout mice.
