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GlossarymTOR pathway (mammalian target of rapamycin pathway)

regulates cell growth and metabolism in response to nutrients

The mTOR pathway, short for the mechanistic target of rapamycin pathway, is a crucial cellular signaling pathway that regulates growth, metabolism, and survival in response to nutrients, growth factors, and other environmental cues. It plays a significant role in various biological processes, including cell proliferation, protein synthesis, and autophagy, and is implicated in conditions like cancer, diabetes, and neurodegenerative diseases.

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research Differential Expression of Phospho-S6 in Hair Follicle Tumors: Evidence of Mammalian Target of Rapamycin Pathway Activation

4 citations, January 2019 in “Journal of cutaneous pathology”

The mTOR pathway may be involved in the development of hair follicle tumors, with higher activity in malignant tumors.

research Frontal Fibrosing Alopecia: A Review of Disease Pathogenesis

2 citations, July 2022 in “Frontiers in Medicine”

The cause of Frontal fibrosing alopecia, a type of hair loss, is complex, likely involving immune responses and genetics, but is not fully understood.

research Topical Metformin as a Novel Therapy for Alopecia Areata Due to Its Immunologic Effects

August 2023 in “Medical Hypotheses”

Metformin, usually used for diabetes, can also help treat hair loss from alopecia areata due to its ability to reduce inflammation and stimulate new hair growth.

research PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds

9 citations, June 2023 in “Cells”

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

research Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition

295 citations, September 2006 in “Cell Cycle”

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 9 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Fin/dut increase in estrogen and autoimmune diseases

in Chat 6 upvotes 2 years ago

The conversation discusses the link between increased estrogen and autoimmune diseases, with a focus on avoiding soy and milk. It also mentions treatments like Minoxidil, finasteride, and RU58841 for hair loss.

community Plant-based Exosomes Efficacy Sourced from South Korea

in Treatment 2 upvotes 6 months ago

Plant-based exosomes for hair loss lack scientific evidence and are considered high-risk with low evidence. Combining PRF with minoxidil and finasteride is suggested as a better option.

community Why Is Only Tressless Talking About Verteporfin? Healing Wounds With Zero Scarring Has Gargantuan Implications For All of Medicine. So What Gives?

in Research/Science 19 upvotes 2 years ago

The potential of verteporfin to heal wounds without scarring; however, despite its promising preclinical trials and coverage from a major media outlet, there is still no official clinical trial result and the drug has only garnered attention from hair loss communities.

community Every research project and treatment hope is failing it‘s insane

in Treatment 16 upvotes 6 years ago

The conversation expresses frustration over the lack of progress in hair loss treatments, with specific mentions of Minoxidil, finasteride, and RU58841. Users discuss the slow development of new treatments and the potential of hair transplants.

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