research The Application of Local Hypobaric Pressure: A Novel Means to Enhance Macromolecule Entry Into the Skin
Local hypobaric pressure can significantly improve drug delivery through the skin.
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research Mechanistic Study of Decreased Skin Penetration Using a Combination of Sonophoresis with Sodium Fluorescein-Loaded PEGylated Liposomes with D-Limonene
Using sonophoresis can make it harder for certain drug-loaded liposomes to get through the skin.
research Mechanism of Transdermal Permeation Promotion of Lipophilic Drugs by Ethosomes
Ethosomes are effective for delivering drugs through the skin by penetrating deeply and targeting hair follicles.
research Advances and Challenges in the Treatment of Skin Diseases with the Transdermal Drug Delivery System
New skin disease treatments using TDDS are improving but face challenges like side effects and high costs.
research In Silico Modelling of Transdermal Delivery of Macromolecule Drugs Assisted by a Skin Stretching Hypobaric Device
The simulation showed that hypobaric pressure improves drug delivery through the skin, but stretching alone doesn't fully explain the increase.
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2 / 2 resultscommunity Are carbohydrates needed for hair growth
A 47-year-old male experienced significant hair loss after losing 37 kg in 6 months on a low-carb diet and started taking biotin, zinc, iron, selenium, and spectral dcn-n. Replies suggest that while carbs are not directly needed for hair growth, they help regulate hormones and nutrient absorption, and rapid weight loss can also contribute to hair loss.
community How come Dut doesn’t cause more brain problems than fin if it inhibits Type 1 5AR?
Dutasteride and finasteride have similar risk profiles despite Dutasteride blocking more types of 5AR in the brain. Some users report no mood issues with either drug, and it is suggested that Dutasteride's larger molecular size may limit its ability to cross the blood-brain barrier.