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In Silico Modelling of Transdermal Delivery of Macromolecule Drugs Assisted by a Skin Stretching Hypobaric Device

research In Silico Modelling of Transdermal Delivery of Macromolecule Drugs Assisted by a Skin Stretching Hypobaric Device

1 citations , November 2022 in “Pharmaceutical research”

The simulation showed that hypobaric pressure improves drug delivery through the skin, but stretching alone doesn't fully explain the increase.

Chitosan Hydrogel as Tissue Engineering Scaffolds for Vascular Regeneration Applications

research Chitosan Hydrogel as Tissue Engineering Scaffolds for Vascular Regeneration Applications

8 citations , May 2023 in “Gels”

Chitosan hydrogels are promising for repairing blood vessels but need improvements in strength and compatibility.

research Mechanism of Transdermal Permeation Promotion of Lipophilic Drugs by Ethosomes

105 citations , April 2017 in “International Journal of Nanomedicine”

Ethosomes are effective for delivering drugs through the skin by penetrating deeply and targeting hair follicles.

research Biological Macromolecule Hydrogel Based on Recombinant Type I Collagen/Chitosan Scaffold to Accelerate Full-Thickness Healing of Skin Wounds

12 citations , September 2023 in “Polymers”

The hydrogel speeds up skin wound healing effectively.

research Topical Administration of Drugs Incorporated in Carriers Containing Phospholipid Soft Vesicles for the Treatment of Skin Medical Conditions

29 citations , December 2021 in “Pharmaceutics”

Phospholipid soft vesicles improve topical drug delivery for better skin condition treatments.

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community How come Dut doesn’t cause more brain problems than fin if it inhibits Type 1 5AR?

in Finasteride/Dutasteride 22 upvotes 1 year ago

Dutasteride and finasteride have similar risk profiles despite Dutasteride blocking more types of 5AR in the brain. Some users report no mood issues with either drug, and it is suggested that Dutasteride's larger molecular size may limit its ability to cross the blood-brain barrier.

community Are carbohydrates needed for hair growth

in Research/Science 26 upvotes 1 year ago

A 47-year-old male experienced significant hair loss after losing 37 kg in 6 months on a low-carb diet and started taking biotin, zinc, iron, selenium, and spectral dcn-n. Replies suggest that while carbs are not directly needed for hair growth, they help regulate hormones and nutrient absorption, and rapid weight loss can also contribute to hair loss.