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GlossaryMonoclonal Antibodies (mAbs)

laboratory-produced molecules that target specific cells or proteins

Monoclonal antibodies (mAbs) are laboratory-produced molecules engineered to serve as substitute antibodies that can restore, enhance, or mimic the immune system's attack on cells. They are designed to bind to specific targets, such as proteins on the surface of cancer cells, making them useful in treating various diseases, including some types of cancer, autoimmune disorders, and infectious diseases.

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research Use of Calcitonin Gene-Related Peptide Monoclonal Antibodies in Patients With Rosacea: An Exploratory Comparative Case Series

April 2023 in “Journal of Investigative Dermatology”

CGRP MAbs treatment for migraines may also improve rosacea symptoms, but more research is needed to confirm its effectiveness and safety.

research Generation of Pax1/PAX1-Specific Monoclonal Antibodies

10 citations, October 2016 in “Monoclonal antibodies in immunodiagnosis and immunotherapy”

Researchers created specific antibodies that detect a protein important in development and various conditions, and can be used for research and diagnosis.

research Localization of Varicella-Zoster Virus Nucleic Acids and Proteins in Human Skin

25 citations, December 1995 in “Neurology”

The research found that chickenpox virus spreads in skin through blood then to skin cells, while shingles virus moves from nerves to hair follicle areas before infecting skin cells.

research Chemotherapy-Induced Iatrogenic Injury of Skin: New Drugs and New Concepts

19 citations, October 2011 in “Clinics in Dermatology”

New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.

research Dermatologic Reactions to Targeted Therapy

15 citations, February 2017 in “Nursing Clinics of North America”

Targeted cancer therapies can cause skin side effects, which should be treated early to help patients' quality of life and treatment adherence.

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community Somebody has gotta try this- HMI-115 reference anti-body

in Treatment 14 upvotes 1 year ago

The potential of using a specific antibody, HMI-115, as a treatment for hair loss alongside traditional treatments such as minoxidil and finasteride. The user suggests trying either a 240 mg or 30 mg dose to see if it works.

community The likely cost of HMI-115, when it comes out

in Technology 12 upvotes 1 year ago

A new potential hair loss treatment called HMI-115, and the cost of this treatment which may be expensive due to production costs but could be competitive with other treatments such as hair transplants.

community An argument for why we should take topical Dutasteride seriously

in Research/Science 85 upvotes 3 years ago

Topical Dutasteride may halt hair loss and effectively treat androgenic alopecia. Combining low-dose oral Dutasteride with topical application could maximize regrowth and minimize side effects.