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GlossaryMonoclonal Antibodies (mAbs)

laboratory-produced molecules that target specific cells or proteins

Monoclonal antibodies (mAbs) are laboratory-produced molecules engineered to serve as substitute antibodies that can restore, enhance, or mimic the immune system's attack on cells. They are designed to bind to specific targets, such as proteins on the surface of cancer cells, making them useful in treating various diseases, including some types of cancer, autoimmune disorders, and infectious diseases.

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research Use of Calcitonin Gene-Related Peptide Monoclonal Antibodies in Patients With Rosacea: An Exploratory Comparative Case Series

April 2023 in “Journal of Investigative Dermatology”

CGRP MAbs treatment for migraines may also improve rosacea symptoms, but more research is needed to confirm its effectiveness and safety.

research Generation of Pax1/PAX1-Specific Monoclonal Antibodies

10 citations, October 2016 in “Monoclonal antibodies in immunodiagnosis and immunotherapy”

Researchers created specific antibodies that detect a protein important in development and various conditions, and can be used for research and diagnosis.

research Loss of ERBB2 and ERBB3 Receptors Impacts Epidermal Differentiation in Mice

July 2024 in “Journal of Investigative Dermatology”

Losing both ERBB2 and ERBB3 receptors in mice causes significant skin problems and inflammation.

research Expression and Distribution Patterns of Spermine, Spermidine, and Putrescine in Rat Hair Follicle

2 citations, November 2017 in “Histochemistry and Cell Biology”

Polyamines are abundant in certain parts of rat hair follicles and may play a key role in hair growth.

research Drug Pipeline Q2 2022: A Downturn in Approvals

August 2022 in “Nature Biotechnology”

Drug approvals slowed in 2Q22, but notable drugs like Amvuttra, Camzyos, and Olumiant were approved.

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community Somebody has gotta try this- HMI-115 reference anti-body

in Treatment 13 upvotes 1 year ago

The potential of using a specific antibody, HMI-115, as a treatment for hair loss alongside traditional treatments such as minoxidil and finasteride. The user suggests trying either a 240 mg or 30 mg dose to see if it works.

community The likely cost of HMI-115, when it comes out

in Technology 11 upvotes 2 years ago

A new potential hair loss treatment called HMI-115, and the cost of this treatment which may be expensive due to production costs but could be competitive with other treatments such as hair transplants.

community An argument for why we should take topical Dutasteride seriously

in Research/Science 85 upvotes 3 years ago

Topical Dutasteride may halt hair loss and effectively treat androgenic alopecia. Combining low-dose oral Dutasteride with topical application could maximize regrowth and minimize side effects.