research Non-histone Methylation of SET7/9 and its Biological Functions
This review examines the role of SET7/9 in non-histone methylation and its implications in various diseases, including cancer, but presents no new clinical results.
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research Proteomic tools for the investigation of human hair structural proteins and evidence of weakness sites on hair keratin coil segments
This study used proteomic techniques to analyze human hair proteins, revealing keratin heterogeneity and identifying posttranslational modifications, such as cysteine trioxidation and methylation.
research Epidermal Stem Cells Are Defined by Global Histone Modifications that Are Altered by Myc-Induced Differentiation
This study found that Myc activation in epidermal stem cells leads to chromatin modifications that promote stem cell exit and differentiation, which can be influenced by HDAC inhibitors like trichostatin A.
research Polycomb repressive complex 2 in adult hair follicle stem cells is dispensable for hair regeneration
This study found that PRC2 plays a non-instructive role in adult hair follicle stem cells, with its loss not affecting quiescence or cell identity, despite upregulation of genes linked to activation.
research Abnormal epigenetic modifications in peripheral blood mononuclear cells from patients with alopecia areata
This study found that DNA methylation and histone modification status were altered in peripheral blood mononuclear cells of patients with alopecia areata, suggesting these changes may contribute to the disease's pathological immune responses.
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