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GlossaryToxic Epidermal Necrolysis (Lyell's syndrome)

severe skin reaction causing widespread cell death and skin detachment

Toxic Epidermal Necrolysis (TEN) is a rare, life-threatening skin condition characterized by widespread skin cell death, leading to the detachment of the epidermis from the underlying dermis. Often triggered by a severe reaction to medications, it presents with symptoms similar to severe burns, including extensive blistering and peeling of the skin, and requires immediate medical attention.

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research Cutaneous and Ocular Sequelae of Stevens-Johnson Syndrome and Lyell Syndrome

13 citations , December 2010 in “Annales de Dermatologie et de Vénéréologie”

The conclusion is that skin, mucous, and eye problems after Stevens-Johnson syndrome and Lyell syndrome significantly affect patients' lives, highlighting the need for comprehensive care and eye check-ups.

research Toxic Epidermal Necrolysis: A Review of Etiology, Diagnosis, and Management

74 citations , September 1980 in “Medical Clinics of North America”

Toxic epidermal necrolysis is a severe skin condition often caused by drugs, with complex treatment and a high risk of death, but survivors usually heal without scars.

Long-Term Complications of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: The Spectrum of Chronic Problems in Survivors Necessitates Multidisciplinary Follow-Up

research Long-Term Complications of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: The Spectrum of Chronic Problems in Survivors Necessitates Multidisciplinary Follow-Up

105 citations , February 2017 in “British Journal of Dermatology”

Survivors of Stevens-Johnson syndrome/toxic epidermal necrolysis need ongoing care for various long-term health problems.

research Autoimmune Polyendocrine Syndrome Type 1: An Italian Survey on 158 Patients

31 citations , May 2021 in “Journal of endocrinological investigation”

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

research Ocular and Mucocutaneous Sequelae Among Survivors of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Togo

6 citations , January 2019 in “Dermatology Research and Practice”

Many survivors of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Togo suffer long-term eye and skin problems.

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