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research AB023. An atypical clinical presentation of alopecia in two patients with systemic lupus erythematosus

March 2021 in “Annals of Translational Medicine”

This report presents two cases of systemic lupus in male patients with a distinct form of alopecia that combines both scarring and non-scarring elements, highlighting the variability in lupus-related hair loss presentations.

Reply to ‘CD123 Immunohistochemistry for Plasmacytoid Dendritic Cells Is Useful in the Diagnosis of Scarring Alopecia’: Three PDC-Related Parameters Are Useful in Differentiating Lupus Alopecia from LPP

research Reply to ‘CD123 immunohistochemistry for plasmacytoid dendritic cells is useful in the diagnosis of scarring alopecia’: three PDC-related parameters are useful in differentiating lupus alopecia from LPP

4 citations , November 2016 in “Journal of Cutaneous Pathology”

This letter discusses three plasmacytoid dendritic cell-related parameters that may help differentiate lupus alopecia from lichen planopilaris, but it reports no new study results.

Qualitative Patient Interview Study in Patients with Systemic Lupus Erythematosus to Assess Patient Perception of Fatigue and Skin-Related Symptoms

research QUALITATIVE PATIENT INTERVIEW STUDY IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS TO ASSESS PATIENT PERCEPTION OF FATIGUE AND SKIN-RELATED SYMPTOMS

May 2025 in “The Journal of Rheumatology”

This study reports that even minimal improvements in SLE-related fatigue and skin symptoms are meaningful to patients, supporting the content validity of the FACIT-Fatigue scale for measuring these effects.

research Clinical and immunologic parameters during thalidomide treatment of lupus erythematosus

64 citations , May 2000 in “International Journal of Dermatology”

This study found that thalidomide increased peripheral lymphocyte counts and reduced inflammation in lupus erythematosus patients, but was associated with polyneuropathy, suggesting careful use in refractory cases.

research Case Report: High Dose Vitamin D & Anti-inflammatory Diet (Systemic Lupus Erythematosus & Alopecia Areata)

April 2023 in “Zenodo (CERN European Organization for Nuclear Research)”

This case study reported significant improvement in autoimmune-related symptoms, including complete hair regrowth, in a patient with systemic lupus erythematosus and alopecia areata after treatment with the LGS Protocol.

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learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Tofacitinib

a JAK inhibitor for alopecia areata and other autoimmune conditions

What is tofacitinib, and why is it discussed in relation to autoimmune-related hair loss such as alopecia areata? Tofacitinib is a prescription JAK inhibitor approved for rheumatoid arthritis, psoriatic arthritis and ulcerative colitis — not for alopecia areata. It is discussed for hair loss because a 2014 case report and a 2016 open-label trial reported regrowth in severe alopecia areata, but that use is off-label, the regrowth relapsed after stopping, and the drug carries an FDA boxed warning.

learn Baricitinib

JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

learn GHK-Cu

Heard alopecia areata leaves scar-like spots? Some peptides are helping those areas regrow hair. Alopecia areata patches usually still have living follicles. Peptides are being studied as a possible add-on, but the evidence is small and early. See a dermatologist for treatment.

learn Salicylic acid

What makes alopecia areata different from other types of hair loss, and can topical Salicylic acid treatments help regrow the affected areas? Alopecia areata is an autoimmune condition, and salicylic acid does not promote hair regrowth.

learn TDM-105795

What types of alopecia or hair loss conditions might TDM-105795 be designed to target based on current research? TDM-105795 may target non-scarring alopecia, particularly androgenetic alopecia.

learn Bimatoprost

Is bimatoprost effective for people with alopecia areata? Bimatoprost may stimulate hair growth but lacks strong evidence for alopecia areata.

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community The Worst Hair Loss Condition You (MAY) have: LPP

48 upvotes 2 years ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community can someone help me identify these pls

in Treatment 10 months ago

The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

community Alopecia Areata Question

2 upvotes 5 years ago

A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.

community Fibrosing alopecia in a pattern distribution

in Research/Science 14 upvotes 2 years ago

A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

community My 15+ Year Hair Loss Journey: DUPA, Recurrent Alopecia Areata, & different dosages of Min / Fin topicals - Advice needed on next steps.

4 upvotes 2 weeks ago

The user has been managing hair loss for over 15 years, using treatments like Minoxidil, Finasteride, and corticosteroids, while experiencing side effects and recurrent Alopecia Areata. They seek advice on progression and potential underlying conditions, questioning if their hair loss is due to an autoimmune issue beyond typical patterns.

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