353 citations
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February 2022 in “Nature Immunology” Long-haul COVID can cause lasting symptoms affecting many body systems and may be linked to ongoing inflammation and immune system issues.
44 citations
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April 2023 in “Frontiers in Molecular Biosciences” The document provides a comprehensive review of long COVID, a condition affecting up to 20% of COVID-19 survivors, characterized by persistent symptoms such as fatigue, cognitive dysfunction, and respiratory issues. It highlights the complexity of long COVID due to its heterogeneous nature and diverse symptoms, with 44% of sufferers unable to return to work. Various phenotypes, including cardiorespiratory, musculoskeletal, and neuropsychiatric clusters, have been identified. Hair loss, particularly telogen effluvium, is reported in 22% of hospitalized individuals. Proposed mechanisms include immune dysregulation, viral persistence, and microbiome alterations. The document underscores the need for further research to understand these mechanisms and develop effective treatments, noting ongoing trials and the potential benefits of vaccination and lifestyle factors in reducing long COVID risk.
25 citations
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January 2022 in “Endocrine journal” Long COVID patients may have hormonal imbalances linked to their symptoms.
13 citations
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April 2023 in “Nature communications” Long COVID patients have more health issues than non-infected people.
6 citations
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May 2022 in “Journal of Infection” Long-COVID symptoms can last more than a year and change over time.