126 citations
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October 1983 in “Journal of The American Academy of Dermatology” This report verifies isotretinoin's significant efficacy in treating severe acne over the past year in the U.S., highlighting the need for careful patient selection and monitoring due to potential side effects.
53 citations
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October 1993 in “Drug Safety” Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.
59 citations
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May 2017 in “Scientific reports” This study found that ZDHHC13 deficiency in mice is associated with abnormal liver function, lipid metabolism issues, and impaired mitochondrial function, highlighting ZDHHC13's regulatory role in liver metabolism.
1 citations
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October 2024 in “The American Journal of Gastroenterology” This case study suggests that the use of the dietary supplement Nutrafol may have led to drug-induced liver injury in a 26-year-old woman, as evidenced by increased liver enzymes and bilirubin levels which improved after stopping the supplement.
January 2026 in “Pediatrics International” This report examines the cautious approach to administering live vaccines to an infant with a heterozygous FOXN1 variant, noting the importance of monitoring TREC levels and immune function indicators in guiding vaccination decisions in such cases.
