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research Emulsion formulation assays based on natural substances stimulating the hair growth and evaluation of its biological activity

June 2021 in “Zenodo (CERN European Organization for Nuclear Research)”

This study evaluated the stability and capillary growth-stimulating activity of emulsions made with natural plant extracts and oils in vivo on guinea pigs, finding that specific hydrophilic/lipophilic balance and globule size contribute to a stable and effective formulation.

Emulsion Formulation Assays Based on Natural Substances Stimulating Hair Growth and Evaluation of Its Biological Activity

research Emulsion formulation assays based on natural substances stimulating the hair growth and evaluation of its biological activity

June 2021 in “World Journal Of Advanced Research and Reviews”

In this study, researchers evaluated emulsions made with natural plant extracts and oils on guinea pigs, finding that a specific hydrophilic/lipophilic balance and globule size led to a stable emulsion and stimulated hair growth.

research Coumarin derivatives, but not coumarin itself, cause skin irritation via topical delivery

15 citations , February 2014 in “Toxicology Letters”

This study found that osthole, a coumarin derivative, demonstrated significantly higher skin accumulation and potential skin irritation compared to coumarin, which showed negligible alterations in protein biomarkers.

research Multi-Approach Assessment of Albizia saponaria Bioactivity Against Dandruff-Related Bacteria and Fungi

March 2026 in “Journal of Hunan University Natural Sciences”

This study evaluated the antimicrobial activity of Albizia saponaria stem bark against microorganisms causing dandruff and fungal alopecia. It found that the hexane fraction exhibited potent antifungal effects comparable to ketoconazole, highlighting its potential as a natural therapeutic for dandruff.

research Are We Ready to Measure Skin Permeation of Modern Antiaging GHK–Cu Tripeptide Encapsulated in Liposomes?

1 citations , January 2025 in “Molecules”

This review reported that while glycyl-L-histidyl-L-lysine tripeptide copper complex (GHK–Cu) has limited skin permeation when used alone, liposomes may enhance its absorption, but there is limited research on this aspect, highlighting a need for further studies.

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community Why is dutasteride's volume of distribution so much bigger than finasteride? Is it more lipophilic and crosses barriers better?

23 upvotes 1 year ago

Dutasteride has a larger volume of distribution than finasteride due to its lipophilic nature, allowing it to concentrate in hydrophobic areas and making it difficult to excrete. A user experiencing hair loss has been using oral finasteride for 10 months with minimal regrowth and is considering switching to dutasteride or adding oral minoxidil.

community Possible natural pp405 solution

in Research/Science 45 upvotes 1 year ago

Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.

community Compounded Dutasteride Absorption

in Finasteride/Dutasteride 2 upvotes 5 months ago

Mixing Dutasteride with MCT oil may improve absorption due to its fat-soluble nature. Users suggest taking it with whole milk or using oil-based capsules for better effectiveness.

community Real world data from Europe shows that DUT is significantly safer than FIN in long term use

531 upvotes 1 year ago

Dutasteride is safer than finasteride for long-term use, with fewer sexual side effects. Users experience better hair regrowth and fewer side effects with dutasteride.

community Why everyone should be using topical Dutasteride

45 upvotes 3 months ago

Topical Dutasteride, especially in a liposomal base, is recommended for enhanced scalp DHT suppression when used with oral Dutasteride. It is suggested to apply it twice a week for effective results without significant systemic impact.

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