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    Did you mean Lipocalin-type Prostaglandin D Synthase?
    Glossary Lipocalin-type Prostaglandin D Synthase

    enzyme involved in producing prostaglandin D2, affecting sleep and hair growth

    Lipocalin-type Prostaglandin D Synthase (L-PGDS) is an enzyme that plays a crucial role in the production of prostaglandin D2, a compound involved in various physiological processes such as sleep regulation, inflammation, and hair growth. Also known as Beta-trace protein, L-PGDS is found in the brain and cerebrospinal fluid, and its levels can be used as a biomarker for certain neurological conditions.

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    Research 10 of 110

    1. Structural and dynamic insights into substrate binding and catalysis of human lipocalin prostaglandin D synthase Journal of Lipid Research · 2013 · 20 citations
    2. High-resolution structures of mutants of residues that affect access to the ligand-binding cavity of human lipocalin-type prostaglandin D synthase Acta Crystallographica Section D-biological Crystallography · 2014 · 5 citations
    3. Structural & functional studies of L-PGDS and SMPDL3A enzymes in lipid signaling family 2019
    4. Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin Frontiers in Physiology · 2021 · 18 citations
    5. Does prostaglandin D<sub>2</sub> hold the cure to male pattern baldness? Experimental Dermatology · 2014 · 57 citations
    6. The prostaglandin synthases, COX-2 and L-PGDS, mediate prostate hyperplasia induced by low-dose bisphenol A Scientific Reports · 2020 · 20 citations
    7. Prostaglandins: Key players in immunomodulation of the nervous system Neural Regeneration Research · 2025 · 3 citations
    8. Ageratum Conyzoides L. Extract Inhibits 5α-Reductase Gene Expression and Prostaglandin D2 Release in Human Hair Dermal Papilla Cells and Improves Symptoms of Hair Loss in Otherwise Healthy Males and Females in an Open Label Pilot Study Journal of cosmetology & trichology · 2021
    9. Divergent proliferation patterns of distinct human hair follicle epithelial progenitor niches in situ and their differential responsiveness to prostaglandin D2 Scientific Reports · 2017 · 21 citations
    10. Tissue Regeneration, Stem Cells, and Wound Healing Journal of Investigative Dermatology · 2012 · 3 citations
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