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    Did you mean Lipocalin-type Prostaglandin D Synthase?
    Glossary Lipocalin-type Prostaglandin D Synthase

    enzyme involved in producing prostaglandin D2, affecting sleep and hair growth

    Lipocalin-type Prostaglandin D Synthase (L-PGDS) is an enzyme that plays a crucial role in the production of prostaglandin D2, a compound involved in various physiological processes such as sleep regulation, inflammation, and hair growth. Also known as Beta-trace protein, L-PGDS is found in the brain and cerebrospinal fluid, and its levels can be used as a biomarker for certain neurological conditions.

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    Research 30 of 124

    1. Structural and dynamic insights into substrate binding and catalysis of human lipocalin prostaglandin D synthase Journal of Lipid Research · 2013 · 20 citations
    2. High-resolution structures of mutants of residues that affect access to the ligand-binding cavity of human lipocalin-type prostaglandin D synthase Acta Crystallographica Section D-biological Crystallography · 2014 · 5 citations
    3. Structural & functional studies of L-PGDS and SMPDL3A enzymes in lipid signaling family 2019
    4. Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin Frontiers in Physiology · 2021 · 18 citations
    5. A prostaglandind-synthase-positive mast cell gradient characterizes scalp patterning Journal of Cutaneous Pathology · 2013 · 6 citations
    6. Oral administration of low-dose bisphenol A promotes proliferation of ventral prostate and upregulates prostaglandin D<sub>2</sub> synthase expression in adult rats Toxicology and Industrial Health · 2015 · 14 citations
    7. Does prostaglandin D<sub>2</sub> hold the cure to male pattern baldness? Experimental Dermatology · 2014 · 57 citations
    8. The prostaglandin synthases, COX-2 and L-PGDS, mediate prostate hyperplasia induced by low-dose bisphenol A Scientific Reports · 2020 · 20 citations
    9. Increased DHT levels in androgenic alopecia have been selected for to protect men from prostate cancer Medical Hypotheses · 2014 · 9 citations
    10. Prostaglandin D2 Inhibits Wound-Induced Hair Follicle Neogenesis through the Receptor, Gpr44 Journal of Investigative Dermatology · 2012 · 68 citations
    11. Prostaglandins: Key players in immunomodulation of the nervous system Neural Regeneration Research · 2025 · 3 citations
    12. Ageratum Conyzoides L. Extract Inhibits 5α-Reductase Gene Expression and Prostaglandin D2 Release in Human Hair Dermal Papilla Cells and Improves Symptoms of Hair Loss in Otherwise Healthy Males and Females in an Open Label Pilot Study Journal of cosmetology & trichology · 2021
    13. Divergent proliferation patterns of distinct human hair follicle epithelial progenitor niches in situ and their differential responsiveness to prostaglandin D2 Scientific Reports · 2017 · 21 citations
    14. Prostaglandin D2 Uses Components of ROS Signaling to Enhance Testosterone Production in Keratinocytes Journal of Investigative Dermatology Symposium Proceedings · 2017 · 9 citations
    15. Tissue Regeneration, Stem Cells, and Wound Healing Journal of Investigative Dermatology · 2012 · 3 citations
    16. CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD2 Cells · 2023
    17. Wound Healing Impairment in Type 2 Diabetes Model of Leptin-Deficient Mice—A Mechanistic Systematic Review International Journal of Molecular Sciences · 2022 · 10 citations
    18. Group IID, IIE, IIF and III secreted phospholipase A2s Biochimica and biophysica acta. Molecular and cell biology of lipids · 2018 · 23 citations
    19. The role of androgen and androgen receptor in skin-related disorders Archives of Dermatological Research · 2012 · 124 citations
    20. Androgen modulation of Wnt/β-catenin signaling in androgenetic alopecia Archives of Dermatological Research · 2018 · 39 citations
    21. Hair keratin KRT81 is expressed in normal and breast cancer cells and contributes to their invasiveness Oncology Reports · 2017 · 24 citations
    22. Beta-trace protein in chronic inflammatory demyelinating polyradiculoneuropathy and Guillain-Barré syndrome – clinical utilization and a new insight into pathophysiological mechanisms Journal of the Neurological Sciences · 2025 · 1 citations
    23. Engineering strategies to enhance the research progress of mesenchymal stem cells in wound healing Stem Cell Research & Therapy · 2025 · 10 citations
    24. Differential transcriptome study on the damage of testicular tissues caused by chronic infection of T. gondii in mice Parasites & Vectors · 2024 · 2 citations
    25. ENZYMES British journal of pharmacology · 2011 · 1 citations
    26. Association between Family History and Male Androgenetic Alopecia with Female Pattern Hair Loss Annals of Dermatology · 2023
    27. Technological Advances in Anti-hair Loss and Hair Regrowth Cosmeceuticals: Mechanistic Breakthroughs and Industrial Prospects Driven by Multidisciplinary Collaborative Innovation Aesthetic Plastic Surgery · 2025
    28. Sebaceous immunobiology - skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations Frontiers in immunology · 2022 · 21 citations
    29. Optimization of photobiomodulation therapy for spinal cord injury: A review Photochemistry and Photobiology · 2025
    30. Interdisciplinarity traditional Chinese medicine microneedles in skin disease treatment: Recent advances and challenges Bioactive Materials · 2025