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      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

      learn Clascoterone

      a novel topical treatment that inhibits DHT on androgen receptors

      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

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      community Since there is so much hype for cosmeRNA and HMI-115...

      in Chat  46 upvotes 3 years ago
      Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.

      community TRT. Pyrilutamide. Ru58841. Help

      in Treatment  3 upvotes 2 years ago
      A 30-year-old man experienced significant hair loss after starting testosterone replacement therapy (TRT), which did not improve with daily finasteride and minoxidil. He is considering restarting TRT and is seeking advice on using pyrilutamide or RU58841 to prevent further hair loss.

      community Starting my Pyrilutamide + ru58841 journey

      in Treatment  11 upvotes 3 years ago
      An individual's journey to treat their severe hair loss condition using the medications Pyrilutamide and RU58841. They will provide regular updates on their progress.

      community Ru-58841 vs KX-826/pyrilutamide while on steroids

      in Finasteride/Dutasteride  6 upvotes 1 year ago
      The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.